CROSBY BAR RESTAURANT
American Traditional, Eclectic/Global: $61+
79 Crosby St.
The Lafayette Street entrance is between Prince and Spring Streets.
Subway: N, R at Prince St.; 6 at Spring St.
The Crosby Bar makes no distinction between bar and restaurant (or restaurant and room-service menus), which means you can eat or drink anywhere in the high-ceilinged space, at any hour of day, and choose from an expansive menu sure to satisfy a variety of tastes. The eclectic cocktail list is intoxicatingly broad, with such esoteric ingredients as mango ice, Bokers bitters, and graham cracker crust.
Reservations: (212) 226-6400
Mediterranean, Spanish: $31-$60
324 Lafayette St.
Subway: Bleecker St. (6)
“GATO is Chef Bobby Flay’s expression of Mediterranean food, drink, and design. The NoHo location is a 100-year-old building and GATO is the first restaurant to reside there. GATO combines its NYC roots with a European sensibility and has a casual approach, a bustling environment, and a dedicated passion to its cuisine.”
Reservations: This will fill very quickly. Open table reservations begin Oct. 20 at midnight. Phone reservations begin Oct. 21 at 10 a.m., (212) 334-6400.
Vietnamese, French: $31-$60
403 Lafayette St.
Subway: Astor Place (6)
“Indochine is a timeless classic that combines stylish ambience with an exotic French-colonial Vietnamese menu. Spring rolls arrive hot and crisp, with all their innards (mushrooms, cellophane noodles, chicken, carrots), sole fish is wrapped in a banana leaf with a rich coconut-milk curry, and following the desserts straddle the East-West fence with equal aplomb, whether you pick roasted banana and sticky rice or a perfect French lemon tart.”
Reservations: (212) 505-5111, Open Table
LAFAYETTE GRAND CAFÉ & BAKERY
French, bakery: $31-$60
380 Lafayette St.
Subway: Bleecker St. 
“Lafayette is an everyday grand café and bakery in [celebration] of French cooking at the corner of Lafayette Street and Great Jones Street in downtown Manhattan. Our market-driven bistro menu is a worldly homage to the genre that spans a variety of regions, from Provence to Normandy to neighboring Mediterranean coasts, offering a re-mastery of traditional dishes we love and some signatures.”
Reservations: This will fill very quickly. Phone reservations begin Oct. 20 at 8 a.m., (212) 533-3000. Open table and online reservations begin Nov. 6 (2 weeks in advance).
American, Chinese: $11-$30
330 Lafayette St.
Subway: Bleecker St. 
“The Noho Star serves eclectic food with an offbeat menu composed of half-American, half-Chinese options. Potato pancakes, layered with wasabi-spiked crème fraîche and tuna sashimi, create a pleasing mix of temperatures, textures, and flavors. Stilton-and-bacon burgers and specials such as braised lamb shank and Maine lobster are supplemented by various vegetarian dishes. Or, you can drop in just for dessert: The colossal sundae is big enough for two.”
Reservations: Noho Star does not take reservations. (212) 925-0070 (for information)
218 Lafayette St
Subway: Spring St (6)
“Osteria Morini is a casual Italian restaurant from Chef Michael White. In Italian, ‘osteria’ means a place where the owner ‘hosts’ guests, and at Osteria Morini, Chef White continues this tradition of hospitality, transforming his first downtown restaurant into an authentic, old-world osteria with soulful food from the Emilia-Romagna region of Northern Italy.”
Reservations: (212) 965-8777, Open Table
SANT AMBROEUS SOHO
265 Lafayette St.
Subway: Prince Street (N,R) or Broadway-Lafayette Street (B,D,F,M)
“An exquisite menu by Milan native, chef Marco Barbisotti, reflects the brand’s culinary vision and historic origins of northern Italy including its signature vitello tonnato, cotoletta alla milanese, and risotti. To complement the traditional Italian cuisine, Sant Ambroeus SoHo offers a robust selection of Italian wines.”
Reservations: (212) 966-2770 or online. Open table reservations available.
SPRING STREET NATURAL
Eclectic, international, vegetarian-friendly, local/organic: $12-$34
62 Spring St.
The entrance is on the corner of Lafayette and Spring Streets. Live jazz starts at 7 p.m.
Subway: 6 at Spring St.
“Chef Craig Meltzer uses organic produce and hormone-free poultry whenever possible, and makes many items (ketchup, bread, whole-wheat pie crusts) in-house. The result is a menu equally appealing to health nuts as it is to the meat-and-potatoes-loving contingent. For vegans, the organic brown rice and vegetable dinner with hijiki seaweed is a standby. For omnivores, there’s Spanish almond-topped organic salmon sprinkled with arugula pesto and paired with peppers and squash. Meltzer selects wines from Europe, Australia and New Zealand, and microbrews like Blue Point and Brooklyn Lager are dispensed from a shiny bronze tap atop the century-old mahogany bar.”
Reservations: (212) 966-0290
THE LIBRARY AT THE PUBLIC THEATER
Pub food, American: $11-$30
425 Lafayette St.
Subway: Astor Place (6)
“Open late nightly for dinner and cocktail service, the hidden-away supper club plays dinner bar, watering hole or backstage lounge to downtown denizens and neighborhood dwellers, theater-goers coming or going, academics and artists alike. Chefs Andrew Carmellini and Zachary Faulisi have created an American menu of bar snacks, shareable appetizers, sandwiches, dinner plates, and desserts sourcing local ingredients and New York influence that is available in The Library.”
Reservations: (212) 539-8777